背景資料 This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing
如果抗體很快(1-2周)會(huì)使用,推薦在4℃保存,這是為了避免反復(fù)凍融對(duì)抗體活性的損害。如果要長期保存則好是在-20℃ or -80℃。關(guān)鍵的一點(diǎn)是要根據(jù)說明書推薦的方式來正確的保存抗體!但是,腹水形式的產(chǎn)品請(qǐng)?jiān)谑盏胶罅⒓磧銎饋!因(yàn)樵擃惍a(chǎn)品含有大量的蛋白酶,長期在4℃保存會(huì)導(dǎo)致抗體的降解!